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Found 2 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 8' and Ligand = 'BDBM50597448'
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597448(CHEMBL5180195)
Affinity DataIC50:  280nMAssay Description:Inhibition of human full length USP8 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597448(CHEMBL5180195)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In DepthDetails PubMed