Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'VHL complex' and Ligand = 'BDBM454848'
TargetVHL complex(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM454848(US10730870, Example 11 | US11512083, Example 11)
Affinity DataIC50:  16.3nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetVHL complex(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM454848(US10730870, Example 11 | US11512083, Example 11)
Affinity DataIC50:  542nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetVHL complex(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM454848(US10730870, Example 11 | US11512083, Example 11)
Affinity DataIC50:  1.56E+3nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent