Found 10 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 1' and Ligand = 'BDBM2579'
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of FLT1 (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human FLT1 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 14.7nMAssay Description:Inhibition of human FLT1 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human FLT1 by Hotspot assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human Flt1 expressed in Sf9 insect cells using Ulight-TK peptide as substrate after 15 mins by LANCE methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataKd: 150nMAssay Description:Binding constant for FLT1 kinase domainMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataKd: 150nMAssay Description:Binding constant for FLT1 kinase domainMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Southeast University
Curated by ChEMBL
Southeast University
Curated by ChEMBL
Affinity DataKd: 11nMAssay Description:Binding affinity to recombinant FLT1 (unknown origin) assessed as dissociation constant by DSF assayMore data for this Ligand-Target Pair