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Found 2 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 1' and Ligand = 'BDBM445247'
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  36.2nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  36.2nMAssay Description:The inhibitory activities of compounds of the invention against VEGFR1 (VEGFR1 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR1 pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent