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Found 3 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50379214'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)
Affinity DataIC50:  29nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)
Affinity DataIC50:  34nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo

US Patent
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)
Affinity DataIC50:  34nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails US Patent