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Found 2 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50421035'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50421035(CHEMBL2087169)
Affinity DataIC50:  3nMAssay Description:Inhibition of N-terminal GST-tagged KDR after 4 hrs by luciferase-luciferin coupled chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50421035(CHEMBL2087169)
Affinity DataIC50:  16nMAssay Description:Inhibition of KDR in human HUVEC cells assessed as inhibition of VEGF-induced ERK phosphorylation incubated for 1 hr prior to VEGF-stimulation measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed