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Found 1 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM5345'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM5345(5-phenyl-N-(pyrimidin-4-yl)-1,3-thiazol-2-amine | ...)
Affinity DataIC50:  36nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed