Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with Target = 'Vasopressin V2 receptor' and Ligand = 'BDBM35714'
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

LigandPNGBDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against arginine vasopressin V2 receptor using [3H]AVP as radioligand in rat adrenal medullaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

LigandPNGBDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against human recombinant arginine vasopressin V2 receptor using [3H]AVP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataKi:  6.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details
PubMed
TargetVasopressin V2 receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataKi:  6.36nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

LigandPNGBDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataKi:  9.42nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

LigandPNGBDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataKi:  9.42nMAssay Description:Concentration which inhibit [3H]AVP binding to human Vasopressin V2 receptor coded HeLa cells by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

LigandPNGBDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataKi:  9.70nMAssay Description:Binding affinity to vasopressin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35714(N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]a...)
Affinity DataKi:  42.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details
PubMed