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Found 3 Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1D' and Ligand = 'BDBM50004633'
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004633((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...)
Affinity DataIC50:  6.60E+3nMAssay Description:Displacement of [3H]nitrendipine from L-type calcium channel of bovine frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004633((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...)
Affinity DataIC50:  6.80E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004633((S)-4-(2-Chloro-phenyl)-6-methyl-2-[4-(2-methyl-im...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of bovine frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed