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Found 2 Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM97514'
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM97514(Roche-Dataset for PDE10A, Compound 6 | US8470820, ...)
Affinity DataIC50:  0.0900nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM97514(Roche-Dataset for PDE10A, Compound 6 | US8470820, ...)
Affinity DataIC50: <1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails US Patent