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Found 1 Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779]' and Ligand = 'BDBM164290'
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM164290(US9669029, 40 5-Methyl-2-[2-(4-thiophen-3-yl-1H-im...)
Affinity DataIC50:  5.70nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent