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Found 6 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50183799'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183799(4-fluoro-N-(4-(methylsulfonyl)phenyl)-N-(1-(3-(6-(...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human GST-PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183799(4-fluoro-N-(4-(methylsulfonyl)phenyl)-N-(1-(3-(6-(...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human GST-PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183799(4-fluoro-N-(4-(methylsulfonyl)phenyl)-N-(1-(3-(6-(...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human GST-PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183799(4-fluoro-N-(4-(methylsulfonyl)phenyl)-N-(1-(3-(6-(...)
Affinity DataIC50:  250nMAssay Description:Ability to block TNFalpha release through inhibition of PDE4 in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183799(4-fluoro-N-(4-(methylsulfonyl)phenyl)-N-(1-(3-(6-(...)
Affinity DataIC50:  250nMAssay Description:Ability to block TNFalpha release through inhibition of PDE4 in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50183799(4-fluoro-N-(4-(methylsulfonyl)phenyl)-N-(1-(3-(6-(...)
Affinity DataIC50:  1.40E+3nMAssay Description:Ability to block TNFalpha release through inhibition of PDE4 in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed