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Found 4 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50346121'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346121(2-(4-(2-(5-chlorothiophen-2-yl)-5-ethyl-6-methylpy...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346121(2-(4-(2-(5-chlorothiophen-2-yl)-5-ethyl-6-methylpy...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human N-terminal His6-tagged PDE4B1 catalytic domain (324 to 691 residues) expressed in baculovirus infected sf9 cells using cAMP as su...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346121(2-(4-(2-(5-chlorothiophen-2-yl)-5-ethyl-6-methylpy...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human N-terminal His6-tagged PDE4B1 catalytic domain (324 to 691 residues) expressed in baculovirus infected sf9 cells using cAMP as su...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346121(2-(4-(2-(5-chlorothiophen-2-yl)-5-ethyl-6-methylpy...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human PDE4B1More data for this Ligand-Target Pair