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Found 9 Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B' and Ligand = 'BDBM34651'
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from human platelets at 1E-7-1E-4M or 1.0E-6 to 1E-3 MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against Phosphodiesterase 3 from heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  2.80E+4nMAssay Description:In vitro inhibitory activity against cAMP phosphodiesterase III in dog aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of low Km cyclic cAMP phosphodiesterase PDE III of guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of fraction III of guinea pig phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous doseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM34651(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Affinity DataIC50:  1.50E+5nMAssay Description:Cardiotonic effect by inhibition of cAMP phosphodiesterase (PDE III)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed