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Found 10 Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B' and Ligand = 'BDBM50000315'
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of phosphodiesterase 3 from human platelets at 1E-7-1E-4M or 1.0E-6 to 1E-3 MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of PDE 3 (phosphodiesterase III) from guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of low Km cyclic cAMP phosphodiesterase PDE III of guinea pig ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of guinea pig phosphodiesterase type IIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of fraction III of guinea pig phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Guinea Pig cAMP specific phosphodiesterase (PDE III); range 4 to 10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of cardiac phosphodiesterase-3 isolated from canine heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed