Found 4 Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A' and Ligand = 'BDBM15296' TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant PDE3A using cAMP as substrate incubated for 20 mins measured by Kinase Glo reagent based microplate reader assayMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human recombinant PDE3A assessed as cGMP hydrolysis after 60 mins by fluorescence polarization assay using tetramethylrhodamine-tagged ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of human recombinant PDE3A assessed as cAMP hydrolysis after 60 mins by fluorescence polarization assay using fluorescein-tagged cAMP as s...More data for this Ligand-Target Pair
