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Found 2 Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50566438'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50566438(CHEMBL4852714)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant full length GST-tagged PDE5A1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50566438(CHEMBL4852714)
Affinity DataEC50:  1.84E+4nMAssay Description:Inhibition of PDE5A in HEK293 cells stably transfected with cGMP biosensor assessed as increase in SNP-induced intracellular cGMP level measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed