Found 3 Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase [537-875]' and Ligand = 'BDBM235742' TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Xuanzhu Pharma
US Patent
Affinity DataIC50: 0.410nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Xuanzhu Pharma
US Patent
Affinity DataIC50: 1.31nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Xuanzhu Pharma
US Patent
Affinity DataIC50: 4.02nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
