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Found 5 Enz. Inhib. hit(s) with Target = 'dCTP pyrophosphatase 1' and Ligand = 'BDBM50241049'
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50241049(CHEMBL463763 | Triptolide, 1 | triptolide)
Affinity DataKi:  1.68E+5nM ΔG°:  -21.5kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo...More data for this Ligand-Target Pair
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50241049(CHEMBL463763 | Triptolide, 1 | triptolide)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of human dCTPase 1More data for this Ligand-Target Pair
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50241049(CHEMBL463763 | Triptolide, 1 | triptolide)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50241049(CHEMBL463763 | Triptolide, 1 | triptolide)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of human recombinant DCTPP1 expressed in Escherichia coli BL21 Star (DE3) using dCTP as substrate by PPiLight assayMore data for this Ligand-Target Pair
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50241049(CHEMBL463763 | Triptolide, 1 | triptolide)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of dCTPase 1 (unknown origin) expressed in Escherichia coli BL21 Star (DE3) using dCTP as substrate by luminescence assayMore data for this Ligand-Target Pair