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Found 8 Enz. Inhib. hit(s) with Target = 'eIF-2-alpha kinase GCN2' and Ligand = 'BDBM614963'
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614963(US20230271939, Compound Example 1 | US20230271939,...)
Affinity DataKi:  1.60nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614963(US20230271939, Compound Example 1 | US20230271939,...)
Affinity DataKi:  1.60nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614963(US20230271939, Compound Example 1 | US20230271939,...)
Affinity DataKi:  2.30nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614963(US20230271939, Compound Example 1 | US20230271939,...)
Affinity DataKi:  2.30nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614963(US20230271939, Compound Example 1 | US20230271939,...)
Affinity DataIC50:  7.20nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614963(US20230271939, Compound Example 1 | US20230271939,...)
Affinity DataIC50:  7.20nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614963(US20230271939, Compound Example 1 | US20230271939,...)
Affinity DataIC50:  103nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614963(US20230271939, Compound Example 1 | US20230271939,...)
Affinity DataIC50:  103nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent