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Found 4 Enz. Inhib. hit(s) with Target = 'eIF-2-alpha kinase GCN2' and Ligand = 'BDBM614972'
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614972(US20230271939, Example 10)
Affinity DataKi:  0.900nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614972(US20230271939, Example 10)
Affinity DataKi:  6.10nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614972(US20230271939, Example 10)
Affinity DataIC50:  19.1nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614972(US20230271939, Example 10)
Affinity DataIC50:  57.3nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent