Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'eIF-2-alpha kinase GCN2' and Ligand = 'BDBM615001'
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM615001(US20230271939, Comp Ex 1)
Affinity DataKi:  0.900nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM615001(US20230271939, Comp Ex 1)
Affinity DataKi:  1.90nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM615001(US20230271939, Comp Ex 1)
Affinity DataIC50:  5.90nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM615001(US20230271939, Comp Ex 1)
Affinity DataIC50:  59.2nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB