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Found 636 with Last Name = 'hui' and Initial = 'y'
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of DPP4 in rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50243396(CHEMBL1231520)
Affinity DataKi:  6nMAssay Description:Inhibition of human AICARFTMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi:  14nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataKi:  180nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50109343(1-Methyl-5-[(S)-5-(3,4,5-trimethoxy-phenyl)-4,5-di...)
Affinity DataKi:  630nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataKi:  780nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50109342(1-Methyl-5-[(R)-5-(3,4,5-trimethoxy-phenyl)-4,5-di...)
Affinity DataKi:  3.69E+3nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of DPP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of POPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012278((2ALPHA,2''BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLAS...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
LigandPNGBDBM50378304(CHEMBL568080)
Affinity DataIC50: <0.0300nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378288(CHEMBL567434)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378305(CHEMBL583417)
Affinity DataIC50: <0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378291(CHEMBL568302)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378289(CHEMBL565705)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378290(CHEMBL568310)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378319(CHEMBL568303)
Affinity DataIC50: <0.0400nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50003691(CHEMBL567624)
Affinity DataIC50: <0.0500nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378292(CHEMBL566106)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50003691(CHEMBL567624)
Affinity DataIC50: <0.0500nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378293(CHEMBL566550)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378294(CHEMBL566972)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378292(CHEMBL566106)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378290(CHEMBL568310)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378295(CHEMBL565490)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378288(CHEMBL567434)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378299(CHEMBL568079)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378298(CHEMBL583421)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378297(CHEMBL566105)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378296(CHEMBL568510)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378212(CHEMBL575450)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378300(CHEMBL565930)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378289(CHEMBL565705)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378301(CHEMBL568311)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378302(CHEMBL583615)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378303(CHEMBL567208)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378304(CHEMBL568080)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378305(CHEMBL583417)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378297(CHEMBL566105)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378293(CHEMBL566550)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378306(CHEMBL567647)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378298(CHEMBL583421)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378307(CHEMBL566329)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378303(CHEMBL567208)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378314(CHEMBL578256)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50378302(CHEMBL583615)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant Cdk2/cyclinAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50378313(CHEMBL567626)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of Cdk2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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