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TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of JAK 3 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  1nMAssay Description:Inhibition of JAK 3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50243388(AT-9283 | US10981896, Compound AT9283)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of JAK 3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50595921(ASN-002 | ASN002 | Asn-002 | Asn002 | EN-3351 | EN...)
Affinity DataIC50:  5nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)
Affinity DataIC50:  6nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50468574(CHEMBL4116008 | US11414410, Example 100)
Affinity DataIC50:  8nMAssay Description:Inhibition of JAK 3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)
Affinity DataIC50:  13nMAssay Description:Inhibition of JAK 3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM277390(3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)ami...)
Affinity DataIC50:  32nMAssay Description:Inhibition of JAK 3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM209866(PF-06651600 | US11111242, Example 5 | US2023034848...)
Affinity DataIC50:  33nMAssay Description:Inhibition of JAK 3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  76nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) measured after 90 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Csir-Indian Institute Of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)
Affinity DataIC50:  428nMAssay Description:Inhibition of N-terminal epitope-tagged JAK3 (781 to 1124 residues) (unknown origin) expressed in Sf21 cells using EQEDEPEGDYFEWLE as substrate in pr...More data for this Ligand-Target Pair
In DepthDetails PubMed