Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50463838'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of recombinant human N-terminal His-tagged JAK3 catalytic domain (795 to 1124 residues) expressed in baculovirus expression system using B...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of JAK3 (unknown origin) in presence of Km ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human JAK3 kinase-domain using Biotin-Lyn-Substrate-2 as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of JAK 3 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)
Affinity DataIC50:  0.710nMAssay Description:Inhibition of recombinant human N-terminal His-tagged JAK3 catalytic domain (795 to 1124 residues) expressed in baculovirus expression system using B...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50463838(CHEMBL4238926)
Affinity DataIC50: <1nMAssay Description:Inhibition of human JAK3 using Biotin-Lyn-Substrate-2 in presence of 1 mM ATP by phosphotyrosine-specific ELISAMore data for this Ligand-Target Pair