TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of thymidin synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 7nMpH: 7.4Assay Description:Inhibition of recombinant human dihydrofolate reductase done at 37 degree C in pH 7.4 with compoundMore data for this Ligand-Target Pair
Affinity DataKi: 94nMpH: 5.5Assay Description:Inhibition of [3H]MTX transport at human PCFT expressed in Chinese hamster R2 cells at pH 5.5 by Dixon plotMore data for this Ligand-Target Pair
Affinity DataKi: 96nMpH: 5.5Assay Description:Displacement of [3H]MTX from human PCFT expressed in Chinese hamster R2 cells at pH 5.5 by Dixon plotMore data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Compound was evaluated for competitive inhibition of recombinant mouse thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 340nMpH: 7.4Assay Description:Inhibition of human thymidylate synthetase at 37 degree C pH 7.4More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 1.54E+3nMpH: 6.8Assay Description:Displacement of [3H]MTX from human PCFT expressed in Chinese hamster R2 cells at pH 6.8 by Dixon plotMore data for this Ligand-Target Pair
Affinity DataKi: 2.54E+3nMpH: 6.8Assay Description:Inhibition of [3H]MTX transport at human PCFT expressed in Chinese hamster R2 cells at pH 6.8 by Dixon plotMore data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 1.91E+4nMAssay Description:Competitive inhibition of human recombinant Serine hydroxymethyltransferase, cytosolic by spectrophotometryMore data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 3.30E+4nMAssay Description:Inhibition of human recombinant Serine hydroxymethyltransferase, cytosolic measured by slope intercepts of mixed-type inhibition against compound con...More data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataKi: 1.86E+5nMAssay Description:Mixed-type inhibition of human recombinant Serine hydroxymethyltransferase, cytosolic measured by Y-axes intercepts of mixed-type inhibition against ...More data for this Ligand-Target Pair