Compile Data Set for Download or QSAR
maximum 50k data
Found 3640 of ic50 for UniProtKB: P10275
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50154006(17-Hydroxy-13-methyl-11-pentyl-1,2,6,7,8,11,12,13,...)
Affinity DataIC50:  0.00900nMAssay Description:Inhibition of AR-dimerization in CHO-K1 cells expressing human androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM25430(4-(2-hydroxyphenyl)-2-(trifluoromethyl)benzonitril...)
Affinity DataIC50:  0.0200nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50073060((9R,10S,11S,13S,17S)-9-Fluoro-11,17-dihydroxy-10,1...)
Affinity DataIC50:  0.0500nMAssay Description:Agonist activity against Human Androgen receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  0.0500nMAssay Description:Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  0.0500nMAssay Description:Activity at androgen receptor in human Saos2 cells assessed as IL6 repressionMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50154006(17-Hydroxy-13-methyl-11-pentyl-1,2,6,7,8,11,12,13,...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human androgen receptor expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238125(CHEMBL4090028)
Affinity DataIC50:  0.190nMAssay Description:Agonist activity at androgen receptor (unknown origin) expressed in African green monkey COS7 cells after 24 hrs by MMTV-promoter driven luciferase r...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM25430(4-(2-hydroxyphenyl)-2-(trifluoromethyl)benzonitril...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at Androgen receptor in human MDA-kb2 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50154003(11-Dodecyl-17-hydroxy-13-methyl-1,2,6,7,8,11,12,13...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human androgen receptor expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50422635(CHEMBL2311179)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human androgen receptor expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50373240(CHEMBL427898)
Affinity DataIC50:  0.200nMAssay Description:Activity at androgen receptor in human Saos2 cells assessed as IL6 repressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238124(CHEMBL4060271)
Affinity DataIC50:  0.200nMAssay Description:Agonist activity at androgen receptor (unknown origin) expressed in African green monkey COS7 cells after 24 hrs by MMTV-promoter driven luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50373235(CHEMBL256769)
Affinity DataIC50:  0.200nMAssay Description:Activity at androgen receptor in human Saos2 cells assessed as IL6 repressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238127(CHEMBL4092535)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of rat liver pyruvate kinase (PK-L) at 7.2 mMMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50373232(CHEMBL257151)
Affinity DataIC50:  0.300nMAssay Description:Activity at androgen receptor in human Saos2 cells assessed as IL6 repressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50403728(CHEMBL2112312)
Affinity DataIC50:  0.300nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataIC50:  0.302nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused androgen receptor (unknown origin) ligand binding domain expressed in UAS-bla GripTite 293 cells as...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238126(CHEMBL4068946)
Affinity DataIC50:  0.320nMAssay Description:Agonist activity at androgen receptor (unknown origin) expressed in African green monkey COS7 cells after 24 hrs by MMTV-promoter driven luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50157822((2R,6S)-4-(3-Trifluoromethyl-phenyl)-4-aza-tricycl...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of androgen dependent human prostate cancer cell MDA-MB-PCa2b proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50366207(CHEMBL1957612)
Affinity DataIC50:  0.470nMAssay Description:Displacement of [17-alpha-methyl-3H]mibolerone from androgen receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238124(CHEMBL4060271)
Affinity DataIC50:  0.490nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in Freestyle293F cells measured after 3 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238126(CHEMBL4068946)
Affinity DataIC50:  0.520nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in Freestyle293F cells measured after 3 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  0.670nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50057651(CHEMBL3326454)
Affinity DataIC50:  0.700nMAssay Description:Binding affinity to human Androgen receptorMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50057651(CHEMBL3326454)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-435 cells after 30 minsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238125(CHEMBL4090028)
Affinity DataIC50:  0.720nMAssay Description:Displacement of [3H]mibolerone from human AR after 3 hrsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238125(CHEMBL4090028)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of Androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238125(CHEMBL4090028)
Affinity DataIC50:  0.720nMAssay Description:Inhibitory activity against rat adenylate kinase II was determined in the presence of AMP, competitive inhibitionMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50154004(11-Decyl-17-hydroxy-13-methyl-1,2,6,7,8,11,12,13,1...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human androgen receptor expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50220643(6-((cyclopropylmethyl)(propyl)amino)-4-(trifluorom...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50220383(4'-methoxy-3-trifluoromethyl-biphenyl-4-carbonitri...)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50373244(CHEMBL258397)
Affinity DataIC50:  0.800nMAssay Description:Activity at androgen receptor in human Saos2 cells assessed as IL6 repressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50594919(Anavar | CHEBI:7820 | Lonavar | NSC-67068 | OXANDR...)
Affinity DataIC50:  0.808nMAssay Description:Inhibition of Androgen receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50068091(CHEMBL3402221)
Affinity DataIC50:  0.840nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50598603(CHEMBL5192412)
Affinity DataIC50:  0.900nMAssay Description:Partial agonist activity at human Androgen receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50154005(17-Hydroxy-13-methyl-11-octyl-1,2,6,7,8,11,12,13,1...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of AR-dimerization in CHO-K1 cells expressing human androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18600(6-[bis(2,2,2-trifluoroethyl)amino]-1,2-dihydroquin...)
Affinity DataKi:  24nM IC50:  1nM EC50:  57nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238127(CHEMBL4092535)
Affinity DataIC50:  1nMAssay Description:Inhibition of Androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238124(CHEMBL4060271)
Affinity DataIC50:  1nMAssay Description:Binding affinity to human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50073104(CHEMBL3410856)
Affinity DataIC50:  1nMAssay Description:Binding affinity to human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50076691(7,7-Dimethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity at human androgen receptor transfected into COS cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50076688(CHEMBL266473 | trans-7-Ethyl-4-trifluoromethyl-5,6...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity at human androgen receptor transfected into COS cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50068096(CHEMBL3402227)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50122645(CHEMBL3623124)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells assessed as inhibition of DHT-induced PSA expression by alkaline phosphatase repor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50220379(3,2'-bis-trifluoromethyl-biphenyl-4-carbonitrile |...)
Affinity DataIC50: >1nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]methyltrienolone from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human androgen receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc by luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50238127(CHEMBL4092535)
Affinity DataIC50:  1nMAssay Description:Inhibition of rat liver pyruvate kinase (PK-L) at 10.7 mMMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50076693(5-Ethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity at human androgen receptor transfected into COS cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50076687(5-Methyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-ox...)
Affinity DataIC50:  1nMAssay Description:In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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