Compile Data Set for Download or QSAR
Found 536 of ki for UniProtKB: P05067
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195684(1-[4-(3-fluoropropoxy)-3-methoxyphenyl]-5-hydroxy-...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50101410((trans,trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4...)
Affinity DataKi:  0.110nMAssay Description:Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50101411(5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...)
Affinity DataKi:  0.130nMAssay Description:Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100131(5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...)
Affinity DataKi:  0.140nMAssay Description:Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100131(5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...)
Affinity DataKi:  0.140nMAssay Description:Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100131(5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100135((E,E)-1-iodo-2,5-bis-(3-hydroxycarbonyl-4-methoxy)...)
Affinity DataKi:  0.170nMAssay Description:Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100135((E,E)-1-iodo-2,5-bis-(3-hydroxycarbonyl-4-methoxy)...)
Affinity DataKi:  0.170nMAssay Description:Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50101413(5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...)
Affinity DataKi:  0.190nMAssay Description:Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50483880(CHEMBL1774642)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Affinity DataKi:  0.208nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50101412(5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...)
Affinity DataKi:  0.270nMAssay Description:Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50483881(CHEMBL1774643)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100131(5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...)
Affinity DataKi:  0.400nMAssay Description:Inhibition constant of compound on ligand binding to aggregates of Amyloid beta was measured by comparing with [125I]-IMSBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50185948(5-hydroxy-2-(4-methylaminophenyl)benzofuran | CHEM...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]IMPY from beta amyloid in human corpse AD brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50481120(Flutemetamol | [3H]-Flutemetamol)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human amyloid beta plaqueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50481120(Flutemetamol | [3H]-Flutemetamol)
Affinity DataKi:  0.740nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50481120(Flutemetamol | [3H]-Flutemetamol)
Affinity DataKi:  0.740nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to human amyloid beta plaqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)
Affinity DataKi:  0.870nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)
Affinity DataKi:  0.870nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50492526(CHEMBL2407616)
Affinity DataKi:  0.895nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50492522(CHEMBL2407622)
Affinity DataKi:  0.895nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100130(4-(6-Iodobenzo[d]thiazol-2-yl)-N,N-dimethylaniline...)
Affinity DataKi:  0.900nMAssay Description:Inhibition constant for amyloid beta compared to [125I]-TZDMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100130(4-(6-Iodobenzo[d]thiazol-2-yl)-N,N-dimethylaniline...)
Affinity DataKi:  0.900nMAssay Description:Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50481609(CHEMBL610504)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I-N-Methyl-4-(4-bromoanilino)phthalimide from beta-amyloid plaques isolated from Alzheimer's disease patient brainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100130(4-(6-Iodobenzo[d]thiazol-2-yl)-N,N-dimethylaniline...)
Affinity DataKi:  0.900nMAssay Description:Inhibition constant for amyloid beta compared to [125I]-TZDMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50173640(4-[(E)-2-(4-Dimethylamino-phenyl)-vinyl]-phenol | ...)
Affinity DataKi:  1.10nMAssay Description:Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50173647((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to amyloid beta (1-42) aggregates in human Alzheimer's disease brain sectionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50173647((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyridine from beta amyloid peptide in brain tissue at 50 uLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50476303(CHEMBL227521)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50173647((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...)
Affinity DataKi:  1.20nMAssay Description:Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50122787(2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50109052((4-Benzothiazol-2-yl-phenyl)-methyl-amine | 4-(ben...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50122787(2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50185947(5-methoxy-2-(4-methylaminophenyl)benzofuran | CHEM...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]IMPY from beta amyloid in human corpse AD brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50402408(CHEMBL2203332)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) aggregatesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50476296(CHEMBL228033)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50479453(CHEMBL519255)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]IMPY from beta-amyloid plaques in AD patient brainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50476855(CHEMBL232112)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]IMPY from beta amyloid plaque in human brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100132(6-Bromo-2-[4-(4-methyl-piperazin-1-yl)-phenyl]-ben...)
Affinity DataKi:  1.60nMAssay Description:Inhibition constant for amyloid beta compared to [125I]-TZDMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100132(6-Bromo-2-[4-(4-methyl-piperazin-1-yl)-phenyl]-ben...)
Affinity DataKi:  1.60nMAssay Description:Inhibition constant for amyloid beta compared to [125I]-TZDMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50481119(AZD-2184 | CHEMBL570378)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50129794(CHEMBL328660 | [4-(6-Bromo-benzothiazol-2-yl)-phen...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50129784(4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylanil...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100133(CHEMBL55401 | [4-(6-Bromo-benzothiazol-2-yl)-pheny...)
Affinity DataKi:  1.90nMAssay Description:Inhibition constant for amyloid beta compared to [125I]-TZDMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50476293(CHEMBL227495)
Affinity DataKi:  1.90nMAssay Description:Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100133(CHEMBL55401 | [4-(6-Bromo-benzothiazol-2-yl)-pheny...)
Affinity DataKi:  1.90nMAssay Description:Inhibition constant for amyloid beta compared to [125I]-TZDMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50481123(CHEMBL570610)
Affinity DataKi:  2nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 536 total ) | Next | Last >>
Jump to: