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TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262079(4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human ALK3 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50560479(CHEMBL4778971)
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50560477(CHEMBL4742906)
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50560468(CHEMBL4786529)
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50560467(CHEMBL4788859)
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50560466(CHEMBL4740381)
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM111123(US10017516, Compound 2 | US9682983, 2)
Affinity DataIC50:  6.5nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM161920(US10017516, Compound 53 | US9682983, 52 | US968298...)
Affinity DataIC50:  6.5nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM111123(US10017516, Compound 2 | US9682983, 2)
Affinity DataIC50:  7nMAssay Description:Inhibition of ALK3 (unknown origin) using Ulight topo IIa (Thr 1342) peptide as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM111123(US10017516, Compound 2 | US9682983, 2)
Affinity DataIC50:  9.10nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM111123(US10017516, Compound 2 | US9682983, 2)
Affinity DataIC50:  9.10nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM143311(US10017516, Compound 11 | US9682983, 11)
Affinity DataIC50:  9.20nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50434751(CHEMBL2385579)
Affinity DataIC50:  10nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262079(4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...)
Affinity DataIC50:  19nMAssay Description:Inhibition of ALK3 (unknown origin) using Ulight topo IIa (Thr 1342) peptide as substrate preincubated for 10 mins followed by substrate addition and...More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262079(4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...)
Affinity DataIC50:  23.4nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM143566(US10017516, Compound 13 | US9682983, 13)
Affinity DataIC50:  29nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM143566(US10017516, Compound 13 | US9682983, 13)
Affinity DataIC50:  29nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
Affinity DataIC50:  34nMAssay Description:Inhibition of GST-tagged human recombinant ALK3 expressed in insect cells using casein as substrate in presence of [gamma-32P]ATP incubated for 45 mi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50:  41nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM143282(US10017516, Compound 10 | US9682983, 10)
Affinity DataIC50:  54nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM143282(US10017516, Compound 10 | US9682983, 10)
Affinity DataIC50:  54nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  55nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM160069(US10017516, Compound 39 | US9682983, 39)
Affinity DataIC50:  57nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM160069(US10017516, Compound 39 | US9682983, 39)
Affinity DataIC50:  57nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM143313(US10017516, Compound 12 | US9682983, 12)
Affinity DataIC50:  62nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM143313(US10017516, Compound 12 | US9682983, 12)
Affinity DataIC50:  62nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM148348(US10017516, Compound 22 | US9682983, 22)
Affinity DataIC50:  78nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM148348(US10017516, Compound 22 | US9682983, 22)
Affinity DataIC50:  78nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM148372(US10017516, Compound 33 | US9682983, 33)
Affinity DataIC50:  89nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM148372(US10017516, Compound 33 | US9682983, 33)
Affinity DataIC50:  89nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM143311(US10017516, Compound 11 | US9682983, 11)
Affinity DataIC50:  92nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataIC50:  95nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataIC50:  95nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596222(CHEMBL5178564)
Affinity DataIC50:  129nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596216(CHEMBL5189688)
Affinity DataIC50:  129nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM148353(US10017516, Compound 24 | US9682983, 24)
Affinity DataIC50:  138nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM148353(US10017516, Compound 24 | US9682983, 24)
Affinity DataIC50:  138nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM111122(US10017516, Compound 17 | US9682983, 1 | US9682983...)
Affinity DataIC50:  146nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM111122(US10017516, Compound 17 | US9682983, 1 | US9682983...)
Affinity DataIC50:  146nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596219(CHEMBL5189461)
Affinity DataIC50:  151nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM148356(US10017516, Compound 27 | US9682983, 27)
Affinity DataIC50:  153nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM148356(US10017516, Compound 27 | US9682983, 27)
Affinity DataIC50:  153nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596215(CHEMBL5183080)
Affinity DataIC50:  161nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596223(CHEMBL5200241)
Affinity DataIC50:  161nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596221(CHEMBL5186575)
Affinity DataIC50:  171nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM518855(US11160797, Example 1 | US11160797, Example 26 | U...)
Affinity DataIC50:  180nMAssay Description:Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM148357(US10017516, Compound 28 | US9682983, 28)
Affinity DataIC50:  180nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM148357(US10017516, Compound 28 | US9682983, 28)
Affinity DataIC50:  180nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetBone morphogenetic protein receptor type-1A(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50596220(CHEMBL5205781)
Affinity DataIC50:  186nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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