Affinity DataKd: 1.30nMAssay Description:Binding affinity to human PIM1 (15 to 313 residues) expressed in bacterial system by KINOMEScan assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 1.40nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
Affinity DataKd: 2.90nMAssay Description:Binding affinity to Pim-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 3.20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 3.20nMAssay Description:Binding constant for PIM1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.20nMAssay Description:Binding constant for PIM1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Average Binding Constant for PIM1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
Affinity DataKd: 27nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding affinity to human PIM1More data for this Ligand-Target Pair
Affinity DataIC50: 49nM Kd: 40nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Competitive binding affinity to PIM1 in presence of ATPMore data for this Ligand-Target Pair
Affinity DataKd: 55nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: 55nMAssay Description:Average Binding Constant for PIM1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 63nMAssay Description:Binding affinity to human partial length Pim1 (A15 to K313 residues ) expressed in bacterial expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
Affinity DataKd: 72nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to PIM1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: >100nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Affinity DataKd: 130nMAssay Description:Binding affinity to PIM1 assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Binding constant for PIM1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding constant for PIM1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human PIM1More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to PIM1More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding constant for PIM1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 207nMAssay Description:Binding affinity to recombinant human full-length N-terminal his-tagged PIM1 expressed in baculovirus expression system using S6K2 peptide as substra...More data for this Ligand-Target Pair
Affinity DataKd: 250nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
Affinity DataKd: 250nMAssay Description:Binding constant for PIM1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 270nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
