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Found 918 of ic50 for UniProtKB: P12821
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50272062((2S,5S)-1-((S)-3-mercapto-2-methylpropanoyl)-5-(3-...)
Affinity DataIC50:  0.0290nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50367879(LISINOPRIL)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human serum ACEMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50367879(LISINOPRIL)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of angiotensin converting enzyme (unknown origin)More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50073120((4S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylam...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant human ACE using Mca-BK2 as substrate preincubated for 10 mins followed by fluorogenic substrate addition and measured after...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50367879(LISINOPRIL)
Affinity DataIC50:  0.100nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from human blood serumMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50175518((3R,7S)-7-((R)-2-Mercapto-3-phenyl-propionylamino)...)
Affinity DataIC50:  0.110nMAssay Description:Inhibitory concentration against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406389
Affinity DataIC50:  0.115nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406391
Affinity DataIC50:  0.132nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50272061((2S,5S)-1-((S)-3-mercapto-2-methylpropanoyl)-5-(ph...)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406942(CHEMBL80665)
Affinity DataIC50:  0.229nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406908(CHEMBL78629)
Affinity DataIC50:  0.251nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406375(CHEMBL35682)
Affinity DataIC50:  0.288nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406380(CHEMBL284734)
Affinity DataIC50:  0.295nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406392
Affinity DataIC50:  0.295nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50084629(1-(3-Benzoylsulfanyl-2-methyl-propionyl)-4-phenyls...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against angiotensin I converting enzyme (ACE)Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406394
Affinity DataIC50:  0.490nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50017125(1-[6-Amino-2-(1-carboxy-3-phenyl-propylamino)-hexa...)
Affinity DataIC50:  0.5nMAssay Description:Compound tested in vitro for inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406369(CHEMBL289022)
Affinity DataIC50:  0.525nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406370(CHEMBL34832)
Affinity DataIC50:  0.525nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50121930(6-(1-Carboxy-3-phenyl-propylamino)-5-oxo-octahydro...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Angiotensin I converting enzyme (ACE) in Bothrops jararaca venomMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50121930(6-(1-Carboxy-3-phenyl-propylamino)-5-oxo-octahydro...)
Affinity DataIC50:  0.603nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406384(CHEMBL34650)
Affinity DataIC50:  0.631nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50520683(CHEMBL4476621)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant ACE using Abz-FRK(Dnp)-P-OH as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406378(CHEMBL431707)
Affinity DataIC50:  0.776nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406942(CHEMBL80665)
Affinity DataIC50:  0.794nMAssay Description:Inhibition of angiotensin I converting enzyme in silicoMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50017122(7-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-1...)
Affinity DataIC50:  0.800nMAssay Description:Compound tested in vitro for inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406372(CHEMBL33025)
Affinity DataIC50:  0.871nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406373(CHEMBL284843)
Affinity DataIC50:  0.891nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50272145((2S,5S)-1-((S)-3-Mercapto-2-methyl-propionyl)-5-(3...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50369775(Mavik | RU-44570 | TRANDOLAPRIL)
Affinity DataIC50:  0.930nMAssay Description:Inhibitory activity against angiotensin I converting enzyme (ACE)Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50073120((4S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylam...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human fully glycosylated ACE C-terminal domain expressed in CHO cells using Cbz-Phe-His-Leu as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50084622((2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoylox...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against angiotensin I converting enzyme (ACE)Checked by AuthorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50146428((S)-1-((1R,5S)-5-Benzoylamino-2-methyl-4-oxo-6-phe...)
Affinity DataIC50:  1nMAssay Description:Inhibition of ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406911(CHEMBL310750)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50130714(1-(3-Mercapto-propionyl)-6-methyl-piperidine-2-car...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from bovine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406387
Affinity DataIC50:  1.10nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50406909(CHEMBL80779)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50367879(LISINOPRIL)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50021129(1-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-p...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme in Hog plasmaMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory concentration against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50017129((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibition against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50367879(LISINOPRIL)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Angiotensin I converting enzyme (ACE) in Bothrops jararaca venomMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Angiotensin I converting enzyme (ACE) in Bothrops jararaca venomMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50367879(LISINOPRIL)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50027142(1-{5-[(Furan-2-carbonyl)-amino]-4-oxo-6-phenyl-hex...)
Affinity DataIC50:  1.40nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50027132(1-[5-Benzoylamino-6-(3,4-dimethoxy-phenyl)-4-oxo-h...)
Affinity DataIC50:  1.40nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50493988(CHEBI:8024 | McN-A-2833 | Perindopril | S-9490)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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