Compile Data Set for Download or QSAR
maximum 50k data
Found 14 of ic50 for UniProtKB: Q9QYN8
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50325065(1-((1-benzyl-1H-tetrazol-5-yl)(4-((4-methylpiperaz...)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM22567(3H]pyrilamine | CHEMBL511 | Dorantamin | Mepyramin...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM22904((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50237870(2-(1,3-bis(2-((S)-2-methylpyrrolidin-1-yl)ethyl)im...)
Affinity DataIC50:  1.90nMAssay Description:Antagonist activity at histamine H3 receptor in rat forebrain assessed as inhibition of [3H]histamine release from synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50237869((+/-)-2-(1,3-bis(2-(2-methylpyrrolidin-1-yl)ethyl)...)
Affinity DataIC50:  4.90nMAssay Description:Antagonist activity at histamine H3 receptor in rat forebrain assessed as inhibition of [3H]histamine release from synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50325066(1-((4-(1H-1,2,4-triazol-1-yl)phenyl)(1-benzyl-1H-t...)
Affinity DataIC50:  9.20nMAssay Description:Antagonist activity at rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50325063(4-((1-benzyl-1H-tetrazol-5-yl)(4-cyclobutyl-1,4-di...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50325064(1-((1-benzyl-1H-tetrazol-5-yl)(4-(methylsulfonyl)p...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50325067(1-((4-((1H-1,2,4-triazol-1-yl)methyl)phenyl)(1-ben...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM600479(US11622967, Example SUVN-G3031)
Affinity DataIC50:  20nMAssay Description:Histamine-3 membranes were prepared from recombinant CHO-k1 cells expressing human histamine-3 receptor or rat histamine-3 receptor. Radioligand (RS)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50237878(2-(1,3-bis(3-(piperidin-1-yl)propyl)imidazolidin-2...)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at histamine H3 receptor in rat forebrain assessed as inhibition of [3H]histamine release from synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50325068(1-(benzofuran-5-yl(1-benzyl-1H-tetrazol-5-yl)methy...)
Affinity DataIC50:  138nMAssay Description:Antagonist activity at rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50253285(4-Bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phe...)
Affinity DataIC50:  2.35E+3nMAssay Description:Displacement of [3H]SMT from histamine H3 receptor in forebrain of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50325040(1-((1-benzyl-1H-tetrazol-5-yl)(phenyl)methyl)-4-me...)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity at rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed