Compile Data Set for Download or QSAR
maximum 50k data
Found 1367 of ic50 for UniProtKB: P47871
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235136(US9359339, 25)
Affinity DataIC50:  0.100nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235135(US9359339, 23)
Affinity DataIC50:  0.200nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235137(US9359339, 27)
Affinity DataIC50:  0.200nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50119552(CHEMBL3617565)
Affinity DataIC50:  0.240nMAssay Description:Displacement of [125I]-glucagon from human glucagon receptor expressed in CHO cells after 4 to 12 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235138(US9359339, 29)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50566470(CHEMBL4857523)
Affinity DataIC50:  0.430nMAssay Description:Antagonist activity at human GCGR expressed in HEK293 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235134(US9359339, 21)
Affinity DataIC50:  0.700nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120365(CHEMBL3616693)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235139(US9359339, 32)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50244265(CHEMBL480113 | trans-4-((4-tert-butylcyclohexyl)(1...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50244238(CHEMBL499372 | trans-4-(((5-(benzyloxy)-1-methyl-1...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50244236(CHEMBL500315 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120319(CHEMBL3616588)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235130(US9359339, 13)
Affinity DataIC50:  1.10nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50358368(CHEMBL1922834)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235131(US9359339, 14)
Affinity DataIC50:  1.30nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120342(CHEMBL3616689)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120364(CHEMBL3616692)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120366(CHEMBL3616694)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50358360(CHEMBL1922708)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235132(US9359339, 15)
Affinity DataIC50:  1.70nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50199486(3-(1-(N-((1r,4r)-4-tert-butylcyclohexyl)-2-(4-(tri...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125]glucagon from human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235142(US9359339, 45)
Affinity DataIC50:  1.80nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50393776(CHEMBL2159349)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120339(CHEMBL3616687)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50244199(CHEMBL458145 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120327(CHEMBL3616675)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120281(CHEMBL3616584)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50244237(CHEMBL448921 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50244235(CHEMBL480692 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50244234(CHEMBL518939 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235129(US9359339, 8)
Affinity DataIC50:  2.20nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50358373(CHEMBL1922839)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50122102(3-Cyano-4-hydroxy-benzoic acid [1-(2,3,5,6-tetrame...)
Affinity DataIC50:  2.30nMAssay Description:In vitro binding affinity for recombinant human glucagon receptor (hGGR) in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235126(US9359339, 3)
Affinity DataIC50:  2.30nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50122102(3-Cyano-4-hydroxy-benzoic acid [1-(2,3,5,6-tetrame...)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity against human glucagon receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235127(US9359339, 4)
Affinity DataIC50:  2.5nMpH: 7.5 T: 2°CAssay Description:A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50393781(CHEMBL2159337)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120374(CHEMBL3616701)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120341(CHEMBL3616688)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50122159(CHEMBL152477 | Cyclopentanecarboxylic acid {4-[(3-...)
Affinity DataIC50:  2.80nMAssay Description:In vitro binding affinity for recombinant human glucagon receptor (hGGR) in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50358366(CHEMBL1922714)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120322(CHEMBL3616591)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120333(CHEMBL3616681)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50120362(CHEMBL3616690)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50075752(4-[5-(4-Chloro-phenyl)-3-(2-isobutoxy-phenyl)-1H-p...)
Affinity DataIC50:  3nMAssay Description:Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50358370(CHEMBL1922836)
Affinity DataIC50:  3.10nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50334486(CHEMBL1643951 | trans-4-((1-(4-tert-butylcyclohexy...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50171818(4-[1-(4-tert-Butyl-cyclohexyl)-3-(4-trifluorometho...)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50122153(CHEMBL156724 | Cyclopentanecarboxylic acid {4-[(3-...)
Affinity DataIC50:  3.40nMAssay Description:In vitro binding affinity for recombinant human glucagon receptor (hGGR) in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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