Affinity DataEC50: 27nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C] labeled AMG accumulation incubated for 15 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 153nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 197nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
Affinity DataEC50: 209nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
Affinity DataEC50: 211nMpH: 7.2 T: 22°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
Affinity DataEC50: 234nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Inhibition of human SGLT1 expressed in xenopus oocytes assessed as inhibition of [14C]AMG uptakeMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 282nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 306nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
Affinity DataEC50: 327nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
Affinity DataEC50: 330nMpH: 7.2 T: 22°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Inhibition of SGLT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 364nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 429nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
Affinity DataEC50: 462nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
Affinity DataEC50: 488nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 550nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 593nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 629nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
Affinity DataEC50: 845nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 860nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 874nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 884nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 910nMAssay Description:Inhibition of SGLT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1.39E+3nMpH: 7.2 T: 22°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Inhibition of SGLT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1.41E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.86E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.90E+3nMAssay Description:Inhibition of SGLT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.03E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.49E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.05E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 3.21E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.58E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 3.81E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+3nMAssay Description:Inhibition of SGLT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 4.09E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 4.69E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 4.93E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 4.96E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.39E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 5.42E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 5.76E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 5.93E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
