Affinity DataKd: 0.0360nMAssay Description:Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli after 1 to 2 mins by surface plasmon resonance spectrosco...More data for this Ligand-Target Pair
Affinity DataKd: 0.0380nMAssay Description:Binding affinity to human MDM2 by by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 0.0450nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0450nMAssay Description:Binding affinity to human MDM2 by by surface plasmon resonace spectroscopyMore data for this Ligand-Target Pair
Affinity DataKd: 0.150nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.220nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 0.257nMAssay Description:Binding affinity to human MDM2 by by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 0.392nMAssay Description:Binding affinity to GST-thrombin-tagged human MDM2 (1 to 188) expressed in Escherichia coli after 1 to 2 mins by surface plasmon resonance spectrosco...More data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:Binding affinity to human MDM2 by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:Binding affinity to human MDM2 by surface plasmon resonance binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.450nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 0.920nMAssay Description:Binding affinity to human DM2 (17 to 125 residues)More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Binding affinity to human MDM2 by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.30nMAssay Description:Inhibition of human MDM2 L33E mutant (14 to 111 residues) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 2.30nMAssay Description:Binding affinity to full length human MDM4 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.70nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.90nMAssay Description:Binding affinity to human MDM2 by by Surface Plasmon Resonace (SPR) spectroscopy binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.20nMAssay Description:Inhibition of p53 binding to MDM2 (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.80nMAssay Description:Binding affinity to HDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Binding affinity to N-terminal TEV/GST-fused human MDM2 (22 to 110 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation consta...More data for this Ligand-Target Pair
Affinity DataKd: 6.30nMAssay Description:Inhibition of p53 binding to MDM2 (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 8.5nMAssay Description:Agonist activity at GPR40 (unknown origin) expressed in mouse A9 cells assessed as inositol phosphate accumulation using [myo-3H]inositol after 1 hr ...More data for this Ligand-Target Pair
Affinity DataKd: 8.60nMAssay Description:Inhibition of p53 binding to MDM2 (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 9.80nMAssay Description:Binding affinity to HDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to recombinant human GST-tagged HDM2More data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Tested for ability to inhibit human erythrocyte carbonic-anhydrase-II- (HCA II) catalyzed carbon dioxide hydrationMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 1 hr by DTT reagent based ...More data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Tested for ability to inhibit human erythrocyte carbonic-anhydrase-II- (HCA II) catalyzed carbon dioxide hydrationMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Agonist activity at human beta-2 adrenergic receptor expressed in human H292 cells assessed as accumulation of intracellular cAMP after 1 hr by Alpha...More data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of p53 binding to MDM2 (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Agonist activity at human beta-2 adrenergic receptor expressed in human H292 cells assessed as accumulation of intracellular cAMP after 1 hr by Alpha...More data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Component deacylation rate constant for interaction with human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Binding affinity to MDM2 (25 to 109 amino acids) (unknown origin) after 30 mins by surface plasmon resosnance analysisMore data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Antagonistic activity against M3 muscarinic receptor in guinea pig left ileum derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
Affinity DataKd: 26nMAssay Description:Binding affinity to human MDM2 expressed in Escherichia coli expression system by using (FITC)-labeled p53 peptide based fluorescence polarization co...More data for this Ligand-Target Pair
Affinity DataKd: 27nMAssay Description:Binding affinity to N-terminal TEV/GST-fused human MDM4 (22 to 110 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation consta...More data for this Ligand-Target Pair
Affinity DataKd: 27nMAssay Description:Antagonistic activity against M3 muscarinic receptor in guinea pig left ileum derived by plotting log(DR - 1) vs log[antagonist]; inactive up to a co...More data for this Ligand-Target Pair
Affinity DataKd: 33nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding affinity to 15N-labeled MDM2 (unknown origin) by 2D 1H-15N HSQC NMR spectroscopic methodMore data for this Ligand-Target Pair
Affinity DataKd: 37.8nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 43nMAssay Description:Antagonistic activity against M3 muscarinic receptor in guinea pig left ileum derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
Affinity DataKd: 53nMAssay Description:Antagonist activity at MDM2 (residues 25 to 109) assessed as inhibition of binding to immobilized p53 (residues 15 to 29) preincubated for 30 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 55nMAssay Description:Binding affinity to human MDM2More data for this Ligand-Target Pair
Affinity DataKd: 55nMAssay Description:Binding affinity to human MDM2 (17 to 125 residues) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 57nMAssay Description:Binding affinity to human MDM2 expressed in Escherichia coli expression system by using (FITC)-labeled p53 peptide based fluorescence polarization co...More data for this Ligand-Target Pair
Affinity DataKd: 57nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair