Affinity DataEC50: 0.0300nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 47nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 51nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nM EC50: 57nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 58nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 72nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 121nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 158nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataEC50: 184nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 194nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nM EC50: 201nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataEC50: 213nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nM EC50: 241nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 10nM EC50: 247nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataEC50: 283nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nM EC50: 315nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataEC50: 327nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nM EC50: 329nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataEC50: 423nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 443nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 19nM EC50: 456nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 16nM EC50: 461nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 18nM EC50: 510nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataEC50: 517nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 14nM EC50: 518nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 29nM EC50: 527nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 13nM EC50: 547nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 15nM EC50: 556nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 9nM EC50: 569nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 20nM EC50: 574nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 74nM EC50: 603nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataEC50: 604nMAssay Description:Inhibition of 11beta-HSD1 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nM EC50: 613nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 9nM EC50: 632nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 62nM EC50: 638nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
