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Report error Found 160 of ic50 for UniProtKB: P25100
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173109(CHEMBL3809093)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50060964((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...)
Affinity DataIC50:  0.150nMAssay Description:Antagonist activity at human alpha1D receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50172997(CHEMBL3808726)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173117(CHEMBL3809319)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173112(CHEMBL3810110)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173118(CHEMBL3808999)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173004(CHEMBL3808896)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50060964((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity at human full-length N-terminal SNAP-tagged alpha1D adrenoceptor expressed in HEK293 cells assessed as inhibition of agonist-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50172999(CHEMBL3808632)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50091350(CHEMBL3582270)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1D adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50172992(CHEMBL3809248)
Affinity DataIC50:  2.60nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50091351(CHEMBL3582269)
Affinity DataIC50: <5nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1D adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50091352(CHEMBL3582268)
Affinity DataIC50: <5nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1D adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50160154(1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-(2,2,2-trifluo...)
Affinity DataIC50:  6.30nMAssay Description:Antagonist activity at human full-length N-terminal SNAP-tagged alpha1D adrenoceptor expressed in HEK293 cells assessed as inhibition of agonist-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419672(CHEMBL1944694)
Affinity DataIC50:  7.90nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50500007(CHEMBL3742276)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at adrenergic alpha1D receptor (unknown origin) by firefly and renilla dual glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50500011(CHEMBL3739533)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at adrenergic alpha1D receptor (unknown origin) by firefly and renilla dual glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173104(CHEMBL3809676)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173003(CHEMBL3187195)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50500006(CHEMBL3742253)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at adrenergic alpha1D receptor (unknown origin) by firefly and renilla dual glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419673(CHEMBL1944695)
Affinity DataIC50:  13nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM31046(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1D adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173101(CHEMBL3808572)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173002(CHEMBL3808408)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50499998(CHEMBL3739762)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at adrenergic alpha1D receptor (unknown origin) by firefly and renilla dual glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50421580(CHEMBL117248)
Affinity DataIC50:  19nMAssay Description:In vitro binding affinity against cloned human alpha-1D-adrenoreceptor receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173110(CHEMBL3808511)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419665(CHEMBL1945299)
Affinity DataIC50:  25nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419664(CHEMBL1945298)
Affinity DataIC50:  25nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419676(CHEMBL1945034)
Affinity DataIC50:  25nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50160154(1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-(2,2,2-trifluo...)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50500003(CHEMBL3742103)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at adrenergic alpha1D receptor (unknown origin) by firefly and renilla dual glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419685(CHEMBL1945290)
Affinity DataIC50:  32nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419678(CHEMBL1945036)
Affinity DataIC50:  32nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173105(CHEMBL3810401)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50091349(CHEMBL3582271)
Affinity DataIC50:  34nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1D adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50500001(CHEMBL3741483)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at adrenergic alpha1D receptor (unknown origin) by firefly and renilla dual glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50499999(CHEMBL3742198)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at adrenergic alpha1D receptor (unknown origin) by firefly and renilla dual glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173000(CHEMBL3808878)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50421597(CHEMBL155327)
Affinity DataIC50:  38nMAssay Description:In vitro binding affinity against human Alpha-1D adrenergic receptor expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50421641(CHEMBL277375)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against radioligand binding to human aAlpha-1D adrenergic receptor, expressed in rat 1 fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419706(CHEMBL1945296)
Affinity DataIC50:  40nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419663(CHEMBL1945297)
Affinity DataIC50:  40nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50421599(CHEMBL155326)
Affinity DataIC50:  41nMAssay Description:In vitro binding affinity against human Alpha-1D adrenergic receptor expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50421602(CHEMBL351542)
Affinity DataIC50:  43nMAssay Description:In vitro binding affinity against human Alpha-1D adrenergic receptor expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50091348(CHEMBL3582272)
Affinity DataIC50:  45nMAssay Description:Displacement of [3H]-Prazosin from human alpha-1D adrenergic receptor transfected in CHO cell membranes after 2 hrs by microplate scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50173005(CHEMBL3809600)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419701(CHEMBL1944692)
Affinity DataIC50:  50nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50419669(CHEMBL1944690)
Affinity DataIC50:  50nMAssay Description:Binding affinity to Alpha-1D adrenoceptor expressed in HEK cells by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Human)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50421593(CHEMBL357129)
Affinity DataIC50:  54nMAssay Description:Binding affinity of compound towards human Alpha-1D adrenergic receptor expressed in rat-1 fibroblast membranesChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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