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Found 68 of ic50 for UniProtKB: P35355
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289087(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289082(3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289084(3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289083(3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289088(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289081(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM22970(2-{1-[(4-bromophenyl)methyl]-5-methoxy-2-methyl-1H...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  10nMAssay Description:Compound was evaluated in vitro for inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289090(CHEMBL162776 | {1-[1-(4-Bromo-benzyl)-5-methoxy-2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289089(2-[1-(4-Chloro-benzyl)-5-methoxy-2-methyl-1H-indol...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289091((S)-4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-in...)
Affinity DataIC50:  20nMAssay Description:Compound was evaluated in vitro for inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260464(CHEMBL4071383)
Affinity DataIC50:  49nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289087(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50:  50nMAssay Description:Compound was evaluated in vitro for inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260465(CHEMBL4101003)
Affinity DataIC50:  53nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289092((R)-4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-in...)
Affinity DataIC50:  60nMAssay Description:Compound was evaluated in vitro for inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289086((2R,3S)-3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  71nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260467(CHEMBL4101946)
Affinity DataIC50:  79nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260470(CHEMBL4063353)
Affinity DataIC50:  99nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260472(CHEMBL4061498)
Affinity DataIC50:  103nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50369676(CHEMBL4161423)
Affinity DataIC50:  150nMAssay Description:Inhibition of COX2 in rat macrophages using arachidonic acid as substrate preincubated with compound for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105290(2-[7-Methoxy-4-(4-methyl-benzyl)-naphthalen-1-yl]-...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105302(2-[7-Methoxy-4-(4-methoxy-benzyl)-naphthalen-1-yl]...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105293(2-(4-Benzyl-7-methoxy-naphthalen-1-yl)-propionic a...)
Affinity DataIC50:  390nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50537507(CHEMBL4638485)
Affinity DataIC50:  420nMAssay Description:Inhibition of Protein kinase C eta expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50289085(CHEMBL159315 | L-748780 | [5-Methoxy-2-methyl-1-(2...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105303(2-[4-(4-Chloro-benzyl)-7-methoxy-naphthalen-1-yl]-...)
Affinity DataIC50:  520nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50487330(CHEMBL4638767)
Affinity DataIC50:  620nMAssay Description:Tested for inhibition of cGMP-dependent protein kinase from bovine lungMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105289(2-[4-(4-Fluoro-benzyl)-7-methoxy-naphthalen-1-yl]-...)
Affinity DataIC50:  740nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  760nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105288(CHEMBL91139 | [4-(4-Chloro-benzyl)-7-methoxy-napht...)
Affinity DataIC50:  880nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105282(2-[4-(4-Ethyl-benzyl)-7-methoxy-naphthalen-1-yl]-p...)
Affinity DataIC50:  1.03E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260477(CHEMBL4083020)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260462(CHEMBL4071496)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105298(2-[4-(2-Chloro-benzyl)-7-methoxy-naphthalen-1-yl]-...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105300(2-[4-(4-Ethoxy-benzyl)-7-methoxy-naphthalen-1-yl]-...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260476(CHEMBL4093268)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105286(2-[4-(4-Fluoro-benzyl)-7-methoxy-naphthalen-1-yl]-...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105284(2-[4-(4-Fluoro-benzyl)-naphthalen-1-yl]-propionic ...)
Affinity DataIC50:  3.50E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105285(2-[4-(4-Chloro-benzyl)-7-methylsulfanyl-naphthalen...)
Affinity DataIC50:  4.20E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105287(2-[4-(4-Chloro-benzyl)-7-methanesulfonyl-naphthale...)
Affinity DataIC50:  4.90E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105294(2-[4-(4-Fluoro-benzyl)-7-methoxy-naphthalen-1-yl]-...)
Affinity DataIC50:  6.38E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105297(2-[4-(4-Acetyl-benzyl)-7-methoxy-naphthalen-1-yl]-...)
Affinity DataIC50:  6.60E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105301(2-[4-(4-tert-Butyl-benzyl)-7-methoxy-naphthalen-1-...)
Affinity DataIC50:  7.50E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50260466(CHEMBL4077676)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50105281(2-[4-(4-Chloro-benzyl)-7-ethyl-naphthalen-1-yl]-pr...)
Affinity DataIC50:  8.20E+3nMAssay Description:In vitro inhibitory concentration against rat Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50537508(CHEMBL4638260)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of Protein kinase C alpha expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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