Compile Data Set for Download or QSAR
maximum 50k data
Found 41 of ec50 for UniProtKB: A0A143MHK7
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50216297(6',7',10,11-tetramethoxyemetan | CHEMBL50588 | Eme...)
Affinity DataEC50:  8.70nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC59 infected in African green monkey Vero cells infected with supernatants from virus-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50216297(6',7',10,11-tetramethoxyemetan | CHEMBL50588 | Eme...)
Affinity DataEC50:  53nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus MR766 infected in HEK293 cells assessed as antiviral activity by measuring NS1 protein expre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50514001(CHEMBL4589719)
Affinity DataEC50:  94nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC59 infected in African green monkey Vero cells assessed as antiviral activity measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  120nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus infected in human NPC assessed as antiviral activity by DAPI-staining based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513993(CHEMBL1630221 | NITD008)
Affinity DataEC50:  137nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus FSS13025/2010 infected in African green monkey Vero cells assessed as antiviral activity mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513993(CHEMBL1630221 | NITD008)
Affinity DataEC50:  137nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus FSS13025/2010 infected in African green monkey Vero cells assessed as antiviral activity by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513993(CHEMBL1630221 | NITD008)
Affinity DataEC50:  137nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus GZ01/2016 infected in African green monkey Vero cells assessed as antiviral activity measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513993(CHEMBL1630221 | NITD008)
Affinity DataEC50:  137nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus GZ01/2016 infected in African green monkey Vero cells assessed as antiviral activity by meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515220(CHEMBL4544781)
Affinity DataEC50:  260nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513990(CHEMBL4469323)
Affinity DataEC50:  300nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC59/Human/2015/Puerto Rico infected in human NSC assessed as antiviral activity measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50088426((1R,2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Affinity DataEC50:  640nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513990(CHEMBL4469323)
Affinity DataEC50:  800nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus H/PAN/2016/BEI-259634 infected in human NSC assessed as antiviral activity measured 72 hrs p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513994(CHEMBL4573335)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC59/Human/2015/Puerto Rico infected in human NSC assessed as antiviral activity measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50000298('2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROX...)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus MR766 infected in African green monkey Vero cells assessed as antiviral activity by Alexa Fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50000298('2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROX...)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus MR766 infected in African green monkey Vero cells assessed as antiviral activity by measurin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50000298('2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROX...)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus MR766 infected in African green monkey Vero cells assessed as antiviral activity by measurin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50000298('2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROX...)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus MR766 infected in African green monkey Vero cells assessed as antiviral activity by methylen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515223(CHEMBL4522602)
Affinity DataEC50:  1.75E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513994(CHEMBL4573335)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus H/PAN/2016/BEI-259634 infected in human NSC assessed as antiviral activity measured 72 hrs p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513991(CHEMBL4454990)
Affinity DataEC50:  2.04E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus MR766 infected in African green monkey Vero E6 cells assessed as antiviral activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50405727(CHEMBL2115031)
Affinity DataEC50:  2.54E+3nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513998(CHEMBL4441902)
Affinity DataEC50:  4.80E+3nMAssay Description:Inhibition of MTase in Zika virus infected in African green monkey Vero cells assessed as antiviral activity incubated for 5 days by inverted microsc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Malaysian P 6-740 infected in African green monkey Vero cells assessed as antiviral activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC-59 infected in human RD cells assessed as antiviral activity by neutral dye based col...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Ugandan MR-766 infected in human RD cells assessed as antiviral activity by neutral dye base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Malaysian P 6-740 infected in human Huh-7 cells assessed as antiviral activity by neutral dy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Ugandan MR-766 infected in African green monkey Vero cells assessed as antiviral activity by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Ugandan MR-766 infected in human Huh-7 cells assessed as antiviral activity by neutral dye b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC-59 infected in human HuH7 cells assessed as antiviral activity by neutral dye based c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC-59 infected in African green monkey Vero cells assessed as antiviral activity by neut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50154375(Adenosine receptor agonist, 16 | Ribavirin | Triba...)
Affinity DataEC50:  2.08E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus MR766 infected in African green monkey Vero cells assessed as antiviral activity after 72 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  3.09E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus infected in African green monkey Vero cells assessed as antiviral activity by DAPI-staining ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515222(CHEMBL4589829)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515219(CHEMBL4456225)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515218(CHEMBL4538994)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515228(CHEMBL4591427)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515225(CHEMBL4464364)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515226(CHEMBL4476535)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515221(CHEMBL4538845)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515227(CHEMBL4465968)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50515224(CHEMBL4473818)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of RNA-dependent RNA polymerase in ZIKV SL0612 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopath...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed