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Found 12 of ki for UniProtKB: Q8NI77
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636877(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataKi:  0.130nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636903(N-(4-(4-(2-(4,4-difluoropiperidin-1-yl)-6- methylp...)
Affinity DataKi:  0.200nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636901(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataKi:  0.210nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636881(N-(4-(4-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataKi:  0.520nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636927(N-(4-(4-(2-(4,4-difluoropiperidin-1- yl)thiazol-4-...)
Affinity DataKi:  0.530nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636926(N-(4-(4-(6-(4,4-difluoropiperidin-1-yl)-4- methylp...)
Affinity DataKi:  0.820nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636871(N-(4-(5-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataKi:  1.5nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636925(N-(4-(4-(2-(4,4-difluoropiperidin-1-yl)-6- methylp...)
Affinity DataKi:  1.70nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636875(N-(4-(5-(6-(4,4-difluoropiperidin-1- yl)pyridin-2-...)
Affinity DataKi:  8.70nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636839(N-(4-(5-(6-morpholinopyridin-2-yl)-4H- 1,2,4-triaz...)
Affinity DataKi:  8.90nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636876(N-(4-(5-(6-morpholinopyridin-2-yl)-1H- imidazol-2-...)
Affinity DataKi:  14nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636928(N-(4-(4-(6-(3,3-difluoroazetidin-1-yl)-4- methylpy...)
Affinity DataKi:  15nMAssay Description:Compound binding kinetics parameters (kon and koff) were determined by the method of global progress curve analysis (GPCA). KIF18A (0.25 nM) was incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent