Compile Data Set for Download or QSAR
maximum 50k data
Found 93 of ic50 for UniProtKB: P15101
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014970(4-(3,5-Difluoro-4-hydroxy-benzyl)-2,4-dihydro-[1,2...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50548688(CHEMBL4764135)
Affinity DataIC50:  39nMAssay Description:Inhibition of bovine adrenal medulla DBH incubated for 25 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50000439(5-Butyl-pyridine-2-carboxylic acid | 5-Butyl-pyrid...)
Affinity DataIC50:  50nMAssay Description:Inhibition of bovine adrenal medulla DBH incubated for 25 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014978(1-(3,5-Difluoro-4-hydroxy-benzyl)-1,3-dihydro-imid...)
Affinity DataIC50:  74nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014978(1-(3,5-Difluoro-4-hydroxy-benzyl)-1,3-dihydro-imid...)
Affinity DataIC50:  74nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (0.060-0.0877).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015622(1-(2-Thiophen-2-yl-ethyl)-1,3-dihydro-imidazole-2-...)
Affinity DataIC50:  114nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015620(1-(2-Thiophen-3-yl-ethyl)-1,3-dihydro-imidazole-2-...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014983(1-(3,5-Difluoro-benzyl)-1,3-dihydro-imidazole-2-th...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015617(1-[2-(5-Methyl-thiophen-2-yl)-ethyl]-1,3-dihydro-i...)
Affinity DataIC50:  491nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014963(1-(3,5-Difluoro-4-hydroxy-benzyl)-1,3-dihydro-benz...)
Affinity DataIC50:  660nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025811(1-(3,5-Dichloro-4-hydroxy-benzyl)-1,3-dihydro-imid...)
Affinity DataIC50:  680nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (0.42-1.1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015621(1-(5-Chloro-thiophen-2-ylmethyl)-1,3-dihydro-imida...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014984(4-(3,5-Difluoro-benzyl)-2,4-dihydro-[1,2,4]triazol...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014983(1-(3,5-Difluoro-benzyl)-1,3-dihydro-imidazole-2-th...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (1.0-1.9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014983(1-(3,5-Difluoro-benzyl)-1,3-dihydro-imidazole-2-th...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014971(1-(3,5-Difluoro-benzyl)-imidazolidine-2-thione | C...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025795(1-(3-Fluoro-4-hydroxy-benzyl)-1,3-dihydro-imidazol...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (0.9-2.2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014967(1-(3,5-Difluoro-benzyl)-1H-tetrazole-5-thiol | CHE...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015619(1-(3-Thiophen-2-yl-propyl)-1,3-dihydro-imidazole-2...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014979(4-(3-Fluoro-benzyl)-2,4-dihydro-[1,2,4]triazole-3-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025806(1-(3-Chloro-4-hydroxy-benzyl)-1,3-dihydro-imidazol...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (1.7-2.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025798(1-[3-(3,5-Dichloro-phenyl)-propyl]-1,3-dihydro-imi...)
Affinity DataIC50:  2.10E+3nMAssay Description:Percent inhibition against bovine Dopamine beta hydroxylase at 10E-4 M concentration of the compound; Range is between (1.8-2.6).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025803(1-(3,4-Dihydroxy-benzyl)-1,3-dihydro-imidazole-2-t...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (1.1-3.8).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014962(1-[3-(4-Hydroxy-phenyl)-propyl]-1,3-dihydro-imidaz...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014962(1-[3-(4-Hydroxy-phenyl)-propyl]-1,3-dihydro-imidaz...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Dopamine beta hydroxylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025793(1-(3,5-Dichloro-benzyl)-1,3-dihydro-imidazole-2-th...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (1.9-3.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014968(1-(4-Hydroxy-benzyl)-1,3-dihydro-imidazole-2-thion...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014968(1-(4-Hydroxy-benzyl)-1,3-dihydro-imidazole-2-thion...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Dopamine beta hydroxylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014968(1-(4-Hydroxy-benzyl)-1,3-dihydro-imidazole-2-thion...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (1.3-4.6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014976(1-(3,5-Difluoro-benzyl)-1H-pyrimidine-2-thione | C...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015624(1-(4-Thiophen-2-yl-butyl)-1,3-dihydro-imidazole-2-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014982(1-(3-Fluoro-benzyl)-imidazolidine-2-thione | CHEMB...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015627(1-(5-Fluoro-thiophen-2-ylmethyl)-1,3-dihydro-imida...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025792(1-[3-(3,5-Difluoro-phenyl)-propyl]-1,3-dihydro-imi...)
Affinity DataIC50:  4.70E+3nMAssay Description:Percent inhibition against bovine Dopamine beta hydroxylase at 10E-4 M concentration of the compound; Range is between (4.2-5.3).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015626(1-Thiophen-2-ylmethyl-1,3-dihydro-imidazole-2-thio...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015625(1-Thiophen-3-ylmethyl-1,3-dihydro-imidazole-2-thio...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014969(1-(3-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (4.9-6.5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014969(1-(3-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015623(1-(5-Methyl-thiophen-2-ylmethyl)-1,3-dihydro-imida...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014959(1-(3,5-Difluoro-benzyl)-1,3-dihydro-benzoimidazole...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014973(2-(3,5-Difluoro-benzyl)-2,4-dihydro-[1,2,4]triazol...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50015618(1-Furan-2-ylmethyl-1,3-dihydro-imidazole-2-thione ...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory activity against bovine adrenal dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025810(1-(3-Bromo-4-hydroxy-benzyl)-1,3-dihydro-imidazole...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between(10-14)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025789(1-(3-Chloro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (10-14).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014980(3-(3,5-Difluoro-benzyl)-1H-pyridine-2-thione | CHE...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014965(2-(3-Fluoro-benzyl)-2,4-dihydro-[1,2,4]triazole-3-...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025498(1-(3-Phenyl-propyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Dopamine beta hydroxylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014981(1-Benzyl-1H-tetrazole-5-thiol | CHEMBL349152)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025791(1-(2,4-Dichloro-benzyl)-1,3-dihydro-imidazole-2-th...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (7-38).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50025499(1-(3-Phenyl-butyl)-1,3-dihydro-imidazole-2-thione ...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Dopamine beta hydroxylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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