Compile Data Set for Download or QSAR
maximum 50k data
Found 21 of ic50 for UniProtKB: P24527
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425166(CHEMBL2313573)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425170(CHEMBL2313569)
Affinity DataIC50:  17nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425148(CHEMBL2313566)
Affinity DataIC50:  19nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425168(CHEMBL2313571)
Affinity DataIC50:  21nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425151(CHEMBL2313563)
Affinity DataIC50:  21nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425164(CHEMBL2313265)
Affinity DataIC50:  21nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425157(CHEMBL2313272)
Affinity DataIC50:  21nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425163(CHEMBL2313266)
Affinity DataIC50:  27nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425149(CHEMBL2313565)
Affinity DataIC50:  49nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425167(CHEMBL2313572)
Affinity DataIC50:  69nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425153(CHEMBL2313561)
Affinity DataIC50:  91nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425171(CHEMBL2313568)
Affinity DataIC50:  100nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425152(CHEMBL2313562)
Affinity DataIC50:  140nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425160(CHEMBL2313269)
Affinity DataIC50:  210nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425169(CHEMBL2313570)
Affinity DataIC50:  230nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425165(CHEMBL2313264)
Affinity DataIC50:  250nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425147(CHEMBL2313567)
Affinity DataIC50:  280nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425154(CHEMBL2313560)
Affinity DataIC50:  420nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  790nMAssay Description:Inhibition of LTA4H in C57BL/6 mouse assessed as reduction in LTB4 production pre-incubated for 30 mins before 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50425150(CHEMBL2313564)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  6.15E+3nMAssay Description:Inhibition of LTA4H in C57BL/6 mouse assessed as reduction in LTB4 production pre-incubated for 30 mins before 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11...More data for this Ligand-Target Pair