Compile Data Set for Download or QSAR
Report error Found 28 of ic50 for UniProtKB: Q9GZT4
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648628BDBM50648628(CHEMBL5611941)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648628BDBM50648628(CHEMBL5611941)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648629BDBM50648629(CHEMBL5613082)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14673BDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataIC50: 2.49E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648631BDBM50648631(CHEMBL5614231)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant human SR incubated for 30 mins by chemiluminescence based luminometer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14673BDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of human SR extracted from Escherichia coli assessed as beta-eliminase activity using L-Ser as substrate by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31147BDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | CHEMBL49...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055464BDBM50055464(CHEMBL3317747)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of serine racemase mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055465BDBM50055465(CHEMBL3317754)
Affinity DataIC50: 5.20E+5nMAssay Description:Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055466BDBM50055466(CHEMBL3317759)
Affinity DataIC50: 6.30E+5nMAssay Description:Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453342BDBM50453342(CHEMBL4205674)
Affinity DataIC50: 8.36E+5nMAssay Description:Inhibition of wild-type serine racemase (unknown origin) assessed as residual activity by measuring D-serine level using Dsd1 as substrate and PLP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055464BDBM50055464(CHEMBL3317747)
Affinity DataIC50: 1.21E+6nMAssay Description:Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14673BDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataIC50: 1.31E+6nMAssay Description:Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055464BDBM50055464(CHEMBL3317747)
Affinity DataIC50: 1.60E+6nMAssay Description:Inhibition of wild-type serine racemase (unknown origin) assessed as residual activity by measuring D-serine level using Dsd1 as substrate and PLP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427212BDBM50427212((2S,3R)-2,3-Dihydroxysuccinic Acid | Meso-Tartrate...)
Affinity DataIC50: 2.82E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648630BDBM50648630(CHEMBL5614081)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of human SR extracted from Escherichia coli assessed as beta-eliminase activity using L-Ser as substrate by spectrophotometer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427205BDBM50427205(CHEMBL2324854)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427209BDBM50427209(CHEMBL1497209)
Affinity DataIC50: 5.02E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427211BDBM50427211(CHEMBL2324857)
Affinity DataIC50: 5.16E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427206BDBM50427206(CHEMBL2324852)
Affinity DataIC50: 5.28E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427210BDBM50427210(CHEMBL2324858)
Affinity DataIC50: 5.72E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074328BDBM50074328(Thiophene-3-carboxylic acid | CHEMBL164585)
Affinity DataIC50: 8.21E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50146456BDBM50146456((2E)-3-(3-hydroxyphenyl)prop-2-enoic acid | trans-...)
Affinity DataIC50: 8.39E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206007BDBM50206007(3-hydroxy-2H-chromen-2-one | 3-Hydroxy-chromen-2-o...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427207BDBM50427207(Crotonate | CROTONIC ACID)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 36181BDBM36181(benzoic acid | benzoate | SODIUM BENZOATE | benzoi...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427208BDBM50427208(CHEMBL554820)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427204BDBM50427204(CHEMBL2324856)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed