Compile Data Set for Download or QSAR
maximum 50k data
Found 121 of ec50 for UniProtKB: Q7TQN8
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at rat GPR119 in GLUTag cells assessed as induction of GLP-1 secretion after 2 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at rat GPR119 in golden hamster HIT-T15 cells assessed as induction of glucose-induced insulin secretion after 2 hrs by A1phaLISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343443(CHEMBL1773283 | tert-butyl 4-(1-(2-fluoro-4-(methy...)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343447(CHEMBL1775169 | tert-butyl 4-(1-(4-(methylsulfonyl...)
Affinity DataEC50:  9.80nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106208(CHEMBL3598101)
Affinity DataEC50:  11nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343452(CHEMBL1773282 | tert-butyl 4-(1-(4-(methylsulfonyl...)
Affinity DataEC50:  15.5nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343445(CHEMBL1773293 | tert-butyl 4-(3-(4-(methylsulfonyl...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343446(CHEMBL1775178 | tert-butyl 4-(1-(2-fluoro-4-(methy...)
Affinity DataEC50:  19.6nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343459(CHEMBL1775174 | cyclopentyl 4-(1-(4-(methylsulfony...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  24nMAssay Description:Agonist activity at rat GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by stead...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106161(CHEMBL3598092)
Affinity DataEC50:  28nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106206(CHEMBL3598099)
Affinity DataEC50:  29nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056010(CHEMBL3326673)
Affinity DataEC50:  31nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056104(CHEMBL3326689)
Affinity DataEC50:  31nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343442(CHEMBL1775179 | isopropyl 4-(1-(2-fluoro-4-(methyl...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343458(CHEMBL1773294 | isopropyl 4-(3-(4-(methylsulfonyl)...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056055(CHEMBL3326688)
Affinity DataEC50:  41nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056009(CHEMBL3326672)
Affinity DataEC50:  41nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343454(CHEMBL1773291 | tert-butyl 4-(3-(4-(methylsulfonyl...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343460(CHEMBL1773288 | tert-butyl 4-(3-methyl-1-(4-(methy...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106154(CHEMBL3598085)
Affinity DataEC50:  45nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50055996(CHEMBL3325846)
Affinity DataEC50:  47nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056105(CHEMBL3326678)
Affinity DataEC50:  49nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106207(CHEMBL3598100)
Affinity DataEC50:  50nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50055994(CHEMBL3325844)
Affinity DataEC50:  50nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343450(CHEMBL1775170 | ethyl 4-(1-(4-(methylsulfonyl)phen...)
Affinity DataEC50:  53nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106160(CHEMBL3598091)
Affinity DataEC50:  54nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50364541(CHEMBL1951011)
Affinity DataEC50:  55nMAssay Description:Agonist activity at rat GPR119 receptor assessed as cAMP production by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106125(CHEMBL3598113)
Affinity DataEC50:  60nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106152(CHEMBL3598083)
Affinity DataEC50:  61nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056007(CHEMBL3326670)
Affinity DataEC50:  63nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106159(CHEMBL3598090)
Affinity DataEC50:  64nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343456(CHEMBL1775176 | neopentyl 4-(1-(4-(methylsulfonyl)...)
Affinity DataEC50:  65nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106126(CHEMBL3598114)
Affinity DataEC50:  65nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106211(CHEMBL3598104)
Affinity DataEC50:  67nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056018(CHEMBL3326681)
Affinity DataEC50:  69nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106210(CHEMBL3598103)
Affinity DataEC50:  72nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056013(CHEMBL3326676)
Affinity DataEC50:  77nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106216(CHEMBL3598109)
Affinity DataEC50:  80nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50341309(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)
Affinity DataEC50:  83nMAssay Description:Agonist activity at rat GPR119 receptor assessed as cAMP production by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50341309(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at rat GPR119 expressed in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343448(CHEMBL1773287 | tert-butyl 4-((1-(2-fluoro-4-(meth...)
Affinity DataEC50:  88nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106157(CHEMBL3598088)
Affinity DataEC50:  89nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106150(CHEMBL3598081)
Affinity DataEC50:  94nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106124(CHEMBL3598112)
Affinity DataEC50:  98nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106217(CHEMBL3598110)
Affinity DataEC50:  101nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056033(CHEMBL3326686)
Affinity DataEC50:  103nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106212(CHEMBL3598105)
Affinity DataEC50:  108nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056003(CHEMBL3326666)
Affinity DataEC50:  109nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106155(CHEMBL3598086)
Affinity DataEC50:  110nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 121 total ) | Next | Last >>
Jump to: