Affinity DataKi: 35nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of LSD1/CoREST (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1 [4-485](Homo sapiens (Human))
Medical University Of South Carolina
Curated by ChEMBL
Medical University Of South Carolina
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of recombinant human LSD1/CoREST complex expressed in Escherichia coli using methylated H3-K4 peptide as substrate by peroxidase-coupled a...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Affinity DataKi: 108nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of recombinant human His-tagged LSD1 (171 to 836 residues)/GST-tagged CoREST (308 to 440 residues) complex using H3K4 peptide substrate by...More data for this Ligand-Target Pair
Affinity DataKi: 146nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 149nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 153nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 156nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 175nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 183nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 193nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 205nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)More data for this Ligand-Target Pair
Affinity DataKi: 212nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 569nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 640nMAssay Description:Inhibition of human LSD1/CoRESTMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assa...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Inhibitory activity against beta-glucosidase of sweet almondMore data for this Ligand-Target Pair
Affinity DataKi: 2.84E+4nMAssay Description:Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataKi: 4.30E+4nMAssay Description:Non-competitive inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated fo...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology
Curated by ChEMBL
European Institute Of Oncology
Curated by ChEMBL
Affinity DataKi: 4.84E+4nMAssay Description:Competitive inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated for 15...More data for this Ligand-Target Pair