Compile Data Set for Download or QSAR
maximum 50k data
Found 65 of ic50 data for polymerid = 5115
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM92338(Wyq16#)
Affinity DataIC50:  230nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50020875(1-Ethyl-4-(N'-isopropylidene-hydrazino)-1H-pyrazol...)
Affinity DataIC50:  700nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50: >1.00E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273546(1-(3,4-Bisdifluoromethoxyphenyl)-3-phenylpropan-1-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336543(5-(4-chlorophenyl)-3-((pyridin-2-ylsulfonyl)methyl...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273544(1-[4-Difluoromethoxy-3-(tetrahydrofuran-3-yloxy)ph...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273574(2-Cyclohexyl-1-[4-difluoromethoxy-3-(tetrahydrofur...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273548(1-(3,4-Bisdifluoromethoxyphenyl)-4-phenylbutan-1-o...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273984(4-(2-Methoxy-4-pentanoylphenoxy)piperidine-1-carbo...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273575(1-[4-Difluoromethoxy-3-(tetrahydrofuran-3-yloxy)ph...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273572(1-(3-Cyclopentyloxy-4-difluoromethoxyphenyl]-3-met...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336542(3-(1-(3-methoxy-4-(pyridin-2-yloxy)phenyl)butyl)qu...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273510(1-[4-Difluoromethoxy-3-(pyridin-2-yloxy)phenyl]but...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273987(1-[3-Methoxy-4-(tetrahydropyran-4-yloxy)phenyl]pen...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336541(CHEMBL1673336 | ethyl 2-(2-(3-(3,4-dichlorophenyl)...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336540(2-((furan-2-ylmethylsulfonyl)methyl)-4-phenylthiaz...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM86219(CAS_5537 | NSC_5537 | Trequinsin)
Affinity DataIC50:  3.90E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336539(1-(4-(difluoromethoxy)-3-(pyridin-2-yloxy)phenyl)-...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273985(1-[3-Methoxy-4-(tetrahydropyran-4-yloxy)phenyl]but...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336538(2-((2-(thiophen-2-yl)thiazol-4-yl)methyl)isoindoli...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336537(CHEMBL1673331 | N-benzyl-5-(4-cyano-3-(methylthio)...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336536(3-((furan-2-ylmethylsulfonyl)methyl)-5-(isoxazol-5...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336535(CHEMBL1673330 | ethyl 2,5-dimethyl-6-(5-phenyl-4H-...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273511(1-[4-Difluoromethoxy-3-(tetrahydropyran-4-yloxy)ph...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273508(2-Cyclohexyl-1-[4-methoxy-3-(tetrahydrofuran-3-ylo...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273331(1-[3-Methoxy-4-(tetrahydrofuran-3-yloxy)phenyl]pen...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273543(CHEMBL457662 | Cyclohexyl-1-[4-difluoromethoxy-3-(...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273547(1-(3,4-Bisdifluoromethoxyphenyl)-2-cyclohexylethan...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM39098(2-(1,3-benzothiazol-2-ylmethyl)-1,1-bis(oxidanylid...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273988(1-[3-Methoxy-4-(tetrahydrofuran-3-yloxy)phenyl]but...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336534(CHEMBL1673329 | N'-(6-tert-butylthieno[3,2-d]pyrim...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273986(4-(4-Butyryl-2-methoxyphenoxy)piperidine-1-carboxy...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM23620(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin...)
Affinity DataIC50:  6.90E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336533(3-allyl-7-(5-(furan-2-yl)-1,3,4-oxadiazol-2-ylthio...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336531(4-methoxy-3-(tetrahydrofuran-3-yloxy)benzaldehyde ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273335(1-[4-Methoxy-3-(tetrahydrofuran-3-yloxy)phenyl]but...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336532(1-(4-methoxy-3-(tetrahydro-2H-pyran-4-yloxy)phenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336515((E)-N'-(pyridin-4-ylmethylene)-2-(5-(pyrrolidin-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336530(1-(4-methoxy-3-(tetrahydrofuran-3-yloxy)phenyl)but...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336529(4-(difluoromethoxy)-3-hydroxybenzaldehyde | CHEMBL...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273920(1-[4-Methoxy-3-(tetrahydropyran-4-yloxy)phenyl]pen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273412(3-Cyclohexyl-1-[4-methoxy-3-(tetrahydrofuran-3-ylo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273507(1-[4-Methoxy-3-(tetrahydrofuran-3-yloxy)phenyl]-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336528(CHEMBL1673317 | S-furan-2-ylmethyl 2-(2,3-dihydrob...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336527(CHEMBL1673318 | N-((2-(thiophen-2-yl)thiazol-4-yl)...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336526(1-(benzo[b]thiophen-3-yl)-3-(2,3-dihydro-1H-inden-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336525(CHEMBL1673320 | ethyl 2-((4-(1,3-dithiolan-2-yl)ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336524(CHEMBL1673322 | N-(2-chlorophenyl)-2-(7-chloroquin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336523(3-benzyl-N-(2-fluorophenyl)-3H-[1,2,3]triazolo[4,5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336522(2-(indolin-1-yl)-N-(5-(thiophen-2-yl)-2,3-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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