Compile Data Set for Download or QSAR
Report error Found 10 of ec50 for UniProtKB: P20813
TargetCytochrome P450 2B6(Human)
University of Washington

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088447BDBM50088447(CHEBI:223316 | (+)-Artemisinin)
Affinity DataEC50:  600nMAssay Description:Induction of CYP2B6 in human hepatocytes after 72 hrs relative to vehicle-treated controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
University of Washington

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370232BDBM50370232(BA-41166E | L-5103 | Rifadin | Rifampicin | RIFAMP...)
Affinity DataEC50:  1.30E+3nMAssay Description:Induction of CYP2B6 activity in human donor hepatocytes assessed as hydroxybupropion formation after 48 hrs by LC/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
University of Washington

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577263BDBM50577263(CHEMBL4850236)
Affinity DataEC50:  1.90E+3nMAssay Description:Induction of CYP2B6 in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
University of Washington

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17292BDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  4.10E+3nMAssay Description:Induction of CYP2B6 activity in human donor hepatocytes assessed as hydroxybupropion formation after 48 hrs by LC/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
University of Washington

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 372346BDBM372346(US10245275, Example 2b | Method A: (R)-4-((1R,3aS,...)
Affinity DataEC50: >5.00E+3nMAssay Description:Induction of CYP2B6 in human hepatocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 2B6(Human)
University of Washington

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575174BDBM50575174(Mavacamten)
Affinity DataEC50:  5.10E+3nMAssay Description:Induction of CYP2B6 in human hepatocytes assessed as mRNA expression incubated for 3 days by RT-RTPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
University of Washington

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249403BDBM50249403(CHEMBL4091821)
Affinity DataEC50: >5.00E+4nMAssay Description:Induction of CYP2B6 in cryopreserved human hepatocytes measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
University of Washington

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451549BDBM50451549(CHEMBL4207737)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of CYP2B6 in human hepatocyte using bupropion as substrate preincubated for 5 days followed by substrate addition and measured after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2B6(Human)
University of Washington

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50437753BDBM50437753(CHEMBL2409564)
Affinity DataEC50: >1.00E+5nMAssay Description:Induction of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
University of Washington

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003659BDBM50003659(5H-dibenzo[b,f]azepine-5-carboxamide | TEGRETOL | ...)
Affinity DataEC50:  1.45E+5nMAssay Description:Induction of CYP2B6 activity in human donor hepatocytes assessed as hydroxybupropion formation after 48 hrs by LC/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed