Compile Data Set for Download or QSAR
Found 15 of kd for UniProtKB: P31749
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM50313650(8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]tr...)
Affinity DataKd:  90nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153703(2-(4-((4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d]im...)
Affinity DataKd:  150nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153702(2-(4-((4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-...)
Affinity DataKd:  410nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153705(Methyl 1-(4-(5-oxo-3-phenyl-5,6-dihydro-1,6-naphth...)
Affinity DataKd:  900nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153707(3-Phenyl-2-(4-((4-(pyrimidin-2-yl)piperazin-1-yl)m...)
Affinity DataKd:  1.10E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153709(7-(4-methylphenyl)-5-phenyl-N-(thiophen-2-ylmethyl...)
Affinity DataKd:  2.20E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153712(5,7-diphenyl-N-(thiophen-2-ylmethyl)-7H-pyrrolo[2,...)
Affinity DataKd:  2.20E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153704(2-(4-((3,4-Dihydroisoquinolin-2(1H)-yl)methyl)phen...)
Affinity DataKd:  6.00E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153714(N-benzyl-7-(4-methylphenyl)-5-phenyl-7H-pyrrolo[2,...)
Affinity DataKd:  6.00E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153706(2-(4-((4-(4-Methoxyphenyl)piperazin-1-yl)methyl)ph...)
Affinity DataKd:  7.20E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153710(7-(4-methylphenyl)-5-phenyl-N-(pyridin-3-ylmethyl)...)
Affinity DataKd:  7.80E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153708(3-Phenyl-2-(4-((4-(tetrahydrofuran-2-carbonyl)pipe...)
Affinity DataKd:  8.00E+3nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153711(7-(4-fluorophenyl)-5-phenyl-N-(pyridin-2-ylmethyl)...)
Affinity DataKd:  2.00E+4nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153713(7-(3-methylphenyl)-5-phenyl-N-(thiophen-2-ylmethyl...)
Affinity DataKd:  9.90E+4nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Homo sapiens (Human))
Technische Universit??t Dortmund

LigandPNGBDBM153715(7-(3-chloro-4-methylphenyl)-5-phenyl-N-(thiophen-2...)
Affinity DataKd:  2.64E+5nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed