Compile Data Set for Download or QSAR
maximum 50k data
Found 40 of ec50 for UniProtKB: Q62226
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50393850(CHEMBL2160030)
Affinity DataEC50:  7.60nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50393851(CHEMBL1221983)
Affinity DataEC50:  8.80nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50393849(CHEMBL2160031)
Affinity DataEC50:  21.9nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50249520(CHEMBL516246 | N-(4-chloro-3-(5-(dimethylamino)-1H...)
Affinity DataEC50:  40nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50393848(CHEMBL2160032)
Affinity DataEC50:  53.8nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50393847(CHEMBL2160033)
Affinity DataEC50:  61.8nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50393846(CHEMBL2160034)
Affinity DataEC50:  118nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50393845(CHEMBL2160035)
Affinity DataEC50:  176nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50249182((1'S,2S,2'R,3R,3aS,6S,7aR,10'S,11'S)-2',3,6,16'-te...)
Affinity DataEC50:  200nMAssay Description:Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421170(CHEMBL2086775 | CHEMBL2086786)
Affinity DataEC50:  300nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421170(CHEMBL2086775 | CHEMBL2086786)
Affinity DataEC50:  400nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421171(CHEMBL2086776)
Affinity DataEC50:  500nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataEC50:  500nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421180(CHEMBL2086785)
Affinity DataEC50:  800nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421180(CHEMBL2086785)
Affinity DataEC50:  800nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421180(CHEMBL2086785)
Affinity DataEC50:  1.00E+3nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50324671(CHEMBL1221984 | Purmorphamine)
Affinity DataEC50:  1.00E+3nMAssay Description:Activation of Shh in mouse Shh Light2 cells after 30 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421180(CHEMBL2086785)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421174(CHEMBL2086779)
Affinity DataEC50:  1.20E+3nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421173(CHEMBL2086778)
Affinity DataEC50:  2.50E+3nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421176(CHEMBL2086781)
Affinity DataEC50:  2.90E+3nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421179(CHEMBL2086784)
Affinity DataEC50:  3.10E+3nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311518(CHEMBL1087150 | N-(4-chlorobenzyl)-2-((2R,6R,E)-5,...)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50249181(CHEMBL473392 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,1...)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of sonic hedgehog pathway in mouse NIH-3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50249181(CHEMBL473392 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,1...)
Affinity DataEC50:  4.00E+3nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421175(CHEMBL2086780)
Affinity DataEC50: >5.00E+3nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421172(CHEMBL2086777)
Affinity DataEC50:  6.60E+3nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311520(CHEMBL1087530 | N-(4-chlorobenzyl)-2-((2R,6R,E)-5,...)
Affinity DataEC50:  7.00E+3nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311521(CHEMBL1081556 | N-(4-chlorobenzyl)-2-((2S,6S,E)-5,...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421177(CHEMBL2086782)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50421178(CHEMBL2086783)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of SHh in mouse Light2 cells assessed as induction of Gli-mediated luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311524(CHEMBL1079558 | N-(4-chlorobenzyl)-2-((2S,6R,E)-5,...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311517((R,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311519(CHEMBL1088172 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311522(CHEMBL1080649 | N-(4-chlorobenzyl)-2-((2S,6S,E)-5,...)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311529((R,E)-N-(4-chlorobenzyl)-2-(5,14-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  3.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311530((R,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  3.10E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311527((S,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311526((S,E)-N-(4-chlorobenzyl)-2-(5,14-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  6.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50311528((S,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  7.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed