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Found 156 of ic50 for UniProtKB: P30989
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50124132(CHEMBL3622802)
Affinity DataIC50:  0.0200nMAssay Description:Displacement of [125I]-Tyr3-NT from human NTS1 receptor expressed in CHOK1 cell membranes incubated for 30 mins by gamma-counting based competitive r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50342242((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)...)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of human NTR1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50370752(CHEMBL1791384)
Affinity DataIC50:  0.140nMAssay Description:Displacement of [125I]Tyr3-NT from human NTS1R expressed in WiDr cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of human NTR1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50370753(CHEMBL1791383)
Affinity DataIC50:  0.180nMAssay Description:Displacement of [125I]Tyr3-NT from human NTS1R expressed in WiDr cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133195(CHEMBL133340 | Compound KK10)
Affinity DataIC50:  0.240nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50440738(CHEMBL2431105)
Affinity DataIC50:  0.240nMAssay Description:Displacement of [125I]-neurotensin from NTR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataIC50:  0.240nMAssay Description:Binding affinity to NTS1 receptor (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50440738(CHEMBL2431105)
Affinity DataIC50:  0.240nMAssay Description:Displacement of [125I]-neurotensin from NTR1 in HUVEC after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133188(CHEMBL336836 | Compound KK17)
Affinity DataIC50:  0.25nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50:  0.25nMAssay Description:Displacement of [125I]Tyr3-neurotensin from human recombinant NTS1 receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133187(CHEMBL133850 | Compound KK3)
Affinity DataIC50:  0.280nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133190(CHEMBL430910 | Compound KK5)
Affinity DataIC50:  0.300nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50240845((S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amin...)
Affinity DataIC50:  0.300nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133201(CHEMBL132524 | Compound KK18)
Affinity DataIC50:  0.300nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130895(CHEMBL408127 | DTPA-Cha(tr-4-Mam)-Pro-Arg-Gly(PipA...)
Affinity DataIC50:  0.300nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130898(CHEMBL408381 | DTPA-Gly(Pip)-Pro-Arg-Gly(PipAm)-Ar...)
Affinity DataIC50:  0.300nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133198(CHEMBL434227 | Compound KK16)
Affinity DataIC50:  0.300nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50370752(CHEMBL1791384)
Affinity DataIC50:  0.320nMAssay Description:Displacement of [125I]Tyr3-NT from human NTS1R expressed in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataIC50:  0.330nMAssay Description:Binding affinity to human NTS1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50342242((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)...)
Affinity DataIC50:  0.330nMAssay Description:Displacement of 125I-[Tyr3]-NT from human NTS1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133200(CHEMBL129953 | Compound KK12)
Affinity DataIC50:  0.340nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133196(CHEMBL337260 | Compound KK6)
Affinity DataIC50:  0.340nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133207(CHEMBL133378 | Compound KK11)
Affinity DataIC50:  0.360nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133206(CHEMBL337644 | Compound KK1)
Affinity DataIC50:  0.380nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50257185((S)-2-((2S,3R)-2-((S)-2-((S)-1-((S)-5-guanidino-2-...)
Affinity DataIC50:  0.383nMAssay Description:Displacement of [125I]I-Tyr(3)NT from human NTR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130873(CHEMBL409477 | DTPA-Arg-Arg-Pro-Tur-Ile-Leu-OH)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130876(CHEMBL404942 | DTPA-DTyr-Glu-Asn-Lys-Pro-Gly(PipAm...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133204(CHEMBL132409 | Compound KK15)
Affinity DataIC50:  0.400nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130899(CHEMBL408638 | DTPA-DLys-Pro-Arg-Gly(PipAm)-Arg-Pr...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133191(CHEMBL132507 | Compound KK7)
Affinity DataIC50:  0.400nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130885(CHEMBL412699 | DTPA-DLys-Pro-Arg-Phe(4-Gu)-Pro-Tyr...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133192(CHEMBL439494 | Compound NT)
Affinity DataIC50:  0.400nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130882(CHEMBL406127 | DTPA-DLys-Pro-Arg-Gly(PipAm)-Arg-Pr...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataIC50:  0.407nMAssay Description:Displacement of [3H]-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-Arg-ProTyr-Ile-Leu-OH Tris(hydrotrifluoroacetate) from NTSR1 in human HT-29...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50370753(CHEMBL1791383)
Affinity DataIC50:  0.410nMAssay Description:Displacement of [125I]Tyr3-NT from human NTS1R expressed in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataIC50:  0.460nMAssay Description:Displacement of [125I]Tyr3-NT from human NTS1R expressed in WiDr cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataIC50:  0.490nMAssay Description:Displacement of [125I]Tyr3-neurotensin from human recombinant NTS1 receptor expressed in CHO cells measured after 60 mins by scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataIC50:  0.490nMAssay Description:Displacement of [125I]Tyr3-neurotensin from human recombinant NT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50370236(CHEMBL1790850)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130886(CHEMBL437288 | alpha-FITC-Gly(Pip)-Pro-Gly(PipAm)-...)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50191594(CHEMBL375002 | Demotensin 4)
Affinity DataIC50:  0.510nMAssay Description:Displacement of [125I]Tyr3-NT from human NTS1R expressed in WiDr cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133202(CHEMBL132794 | Compound KK4)
Affinity DataIC50:  0.510nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133194(CHEMBL133849 | Compound KK2)
Affinity DataIC50:  0.520nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50133199(CHEMBL339139 | Compound KK9)
Affinity DataIC50:  0.590nMAssay Description:Evaluated for binding affinity by inhibiting binding of [125I]-Tyr(3)-NT to human Neurotensin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130875(CHEMBL386387 | DTPA-DTyr-Glu-Asn-Lys-Pro-Gly(PipAm...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130883(CHEMBL406456 | epsilon-FITC-DLys-Pro-Gly(PipAm)-Ar...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity towards neurotensin receptor in membranes prepared from HT-29 cell line, relative to [111In]-labeled neurotensin peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50130880(CHEMBL407196 | NT(1-13) | neurotensin | pGlu-Leu-T...)
Affinity DataIC50:  0.620nMAssay Description:Displacement of [125I]Tyr3-NT from human NTS1R expressed in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50191591(CHEMBL219862 | Demotensin 3)
Affinity DataIC50:  0.660nMAssay Description:Displacement of [125I]Tyr3-NT from human NTS1R expressed in WiDr cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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